abstract |
The present inventor has found that in cancer diseases, cancer cells having a high expression level (production amount) of fibrillarin have a poor prognosis (low survival rate). We also found that the growth of cancer cells can be suppressed by suppressing the expression level (production amount) of fibrillarin. As a result, by using the agent for suppressing the expression or activity of fibrillarin of the present invention, it has become possible to suppress the growth of cancer cells having a poor prognosis and treat cancer diseases. Representative examples of agents that suppress the expression or activity of fibrillarin include siRNA, shRNA, and antisense. |