http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2020054444-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-173 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-173 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
| filingDate | 2019-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2020054444-A1 |
| titleOfInvention | Production method and application of guanosine derivative having a fluorine atom-containing functional group at the 8-position |
| abstract | PROBLEM TO BE SOLVED: To develop a technique capable of stabilizing a higher-order structure of a nucleic acid and using it for analysis of the nucleic acid structure. SOLUTION: A guanosine derivative compound represented by Chemical formula 1. In the formula, one of R1 and R2 is represented by H, the other is represented by one of H, OH, OCH3, and F, R3 is represented by a detection functional group having 19F, and R4 is represented by a detection functional group. , Represented by an amine protecting group, R5 is represented by a hydroxyl protecting group, and R6 is represented by an introducing group for introduction into a nucleic acid oligomer. This guanosine derivative compound can be introduced as a part of the nucleic acid sequence, and the introduced nucleic acid oligomer stabilizes the higher-order structure in the nucleic acid and enables dynamic detection by 19F NMR. be. [Chemical formula 1] [Selection diagram] Fig. 1 |
| priorityDate | 2018-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.