| abstract |
General formula (1) [During the ceremony, A is a optionally substituted benzene ring. B is an aryl that may be substituted or a heteroaryl that may be substituted. X is an oxygen atom or a sulfur atom. Y is a nitrogen atom or a carbon atom. R 1 is either independently of one another are lower alkyl, two of R 1 are bonded to each other, may form a spiro ring or a crosslinked structure, or two of R 1 are bonded to each other, A saturated condensed heterocycle may be formed together with carbon atoms and nitrogen atoms constituting a ring containing Y. p is 0, 1, or 2. Alternatively, (R 1 ) p is oxo. The compound represented by, a salt thereof, or a prodrug thereof is provided as an effective compound for the prevention and / or treatment of fibrosis. |