http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2019168125-A1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate | 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2019168125-A1 |
titleOfInvention | Development of new in vivo receptor visualization technology based on the chemical cross-link method |
abstract | The present disclosure is a method for labeling a biological sample. (A) A step of applying an immobilizing agent to a cell-containing biological sample, and (b) a step of applying a labeling agent to the cell-containing biological sample. (The steps (a) and (b) may be performed first, or the steps (a) and (b) may be performed at the same time). here, The labeling agent has at least one reactive group that reacts with a ligand for a cell surface receptor, a labeling substance and an immobilizing agent. Some cells contained in the cell-containing biological sample contain the cell surface receptor. The cell surface receptor has at least one reactive group that reacts with the immobilizing agent and a ligand binding site. The immobilizing agent reacts with the reactive group of the labeling agent and the reactive group of the cell surface receptor to form a covalent bond, thereby linking the labeling agent with the cell surface receptor. It provides a method for labeling a biological sample. |
priorityDate | 2018-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 444.