http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2018155451-A1

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filingDate 2018-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2018155451-A1
titleOfInvention Nucleic acid compounds and oligonucleotides
abstract The present invention provides non-specific binding of a nucleic acid compound represented by the formula (I) or (II), which hardly forms a non-Watson-Crick type base pair, to a nucleic acid containing the nucleic acid compound and other than a target nucleic acid It is an object of the present invention to provide an oligonucleotide having a reduced amount. In the nucleic acid compound according to the present invention, the carbonyl group at the 2-position of the pyrimidine base is converted into a functional group (X1 and X2 independently represent S or Se), and the 2′- and 4′-positions have a specific structure. It is characterized by being crosslinked. The oligonucleotide according to the present invention is characterized in that at least one of the thymidine and uridine is the nucleic acid compound.
priorityDate 2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 29.