http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2018124119-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-7051 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2018124119-A1 |
titleOfInvention | Method for detecting chromosomal abnormalities and evaluating inducibility |
abstract | The present invention comprises a step of adding and culturing an anti-CD3 antibody to T lymphocytes derived from human pluripotent stem cells, and a step of detecting a chromosomal abnormality in the T lymphocytes cultured in the above steps, A method for detecting a chromosomal abnormality is provided. In addition, a step of adding and culturing an anti-CD3 antibody to T lymphocytes derived from human pluripotent stem cells, a step of adding a test substance to the T lymphocytes cultured in the above step, in a T lymphocyte after addition of the test substance Characterized in that it comprises the steps of measuring the frequency of occurrence of chromosomal abnormalities, and comparing the frequency of occurrence of chromosomal abnormalities with the reference frequency of the control group to evaluate the inducibility of chromosomal abnormalities, Provided is a method for evaluating the inducibility of a chromosomal abnormality by a test substance. |
priorityDate | 2016-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.