http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2018097296-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-344 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2018097296-A1 |
| titleOfInvention | Chemically modified siRNA |
| abstract | The object of the present invention is a chemically modified siRNA in which polydeoxyadenylic acid is added to the 5 ′ end of the sense strand, which has high resistance to RNase when combined with schizophyllan, and effectively exhibits RNAi activity. It is to provide the chemically modified siRNA shown. In the modified siRNA in which polydeoxyadenylic acid is added to the 5 ′ end of the sense strand, the dinucleotide sequences of CA, UA, and UG in the base sequence of the sense strand, and the 8th and later from the 5 ′ end side of the antisense strand By subjecting the CA, UA, and UG dinucleotide sequences to specific chemical modifications, the above problem can be solved. |
| priorityDate | 2016-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 265.