abstract |
Provision of a nucleic acid strand capable of efficiently delivering an antisense oligonucleotide into a living body. A nucleic acid complex comprising a first nucleic acid strand and a second nucleic acid strand, wherein the first nucleic acid strand comprises a base sequence capable of hybridizing to at least a portion of a target transcript, the first nucleic acid The strand has an antisense effect on the target transcript, the second nucleic acid strand comprises a complementary region comprising a base sequence complementary to the first nucleic acid strand, the 5 'end of the complementary region and And / or at least one overhang region located at the 3 'end, wherein the first nucleic acid strand is annealed to a complementary region in the second nucleic acid strand. |