abstract |
An object of the present invention is to provide a novel compound which has CGRP receptor antagonistic activity and is useful for the treatment of various diseases mediated by CGRP receptor. That is, the present invention relates to a pyrrolidine derivative represented by the following formula (I) or a pharmacologically acceptable salt thereof. In the formula, W is a ring, X is a carbon atom or the like, Y 1 to Y 4 are a carbon atom or the like, and R 1 to R 7 are an alkyl or the like. The compounds of the present invention or pharmacologically acceptable salts thereof have excellent CGRP receptor antagonistic activity and are useful as therapeutic agents for various diseases mediated by CGRP receptors. |