Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-173 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6853 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 |
filingDate |
2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-WO2017222056-A1 |
titleOfInvention |
T cell receptor and B cell receptor repertoire analysis system using one-step reverse transcription template switch PCR |
abstract |
The present invention relates to a method for analyzing a repertoire of a variable region of a T cell receptor (TCR) or a B cell receptor (BCR) of a subject, comprising: (1) from RNA obtained from the subject, Providing a nucleic acid sample comprising a plurality of types of T cell receptor (TCR) or B cell receptor (BCR) nucleic acid sequences amplified using step reverse transcription template switching PCR; and (2) contained in the nucleic acid sample. And (3) calculating the appearance frequency of each gene or a combination thereof based on the determined nucleic acid sequence, and deriving the TCR or BCR repertoire of the subject. Provide a way. |
priorityDate |
2016-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |