http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017200087-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2017-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2017200087-A1 |
| titleOfInvention | Novel 5H-pyrrolo [2,3-d] pyrimidin-6 (7H) -one derivatives |
| abstract | The present invention shows an inhibitory action on at least one selected from the group consisting of Akt kinase, Rsk kinase, and S6K kinase, and / or a cell growth inhibitory effect, and prevents and / or prevents diseases associated with the kinase, particularly cancer. Provided is a compound represented by the following formula (I) or a salt thereof which is useful as a therapeutic agent. [Where: R 1 is an optionally substituted 4- to 6-membered monocyclic unsaturated heterocyclic group having 1 to 3 heteroatoms selected from N, S and O; R 2 is a hydrogen atom or the like; R 3 , R 4 and R 5 are the same or different and are a hydrogen atom or the like; R 6 is a hydrogen atom or the like; R 7 and R 8 are the same or different and are a hydrogen atom or the like; X 1 and X 2 are the same or different and are N or CR 9 , R 9 is a hydrogen atom or the like; X 3 is N or CH when the broken line part (---) is a single bond, and is C when the broken line part is a double bond. However, at least one of X 1 and X 2 is N. ] |
| priorityDate | 2016-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.