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filingDate 2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2017082227-A1
titleOfInvention Biosensor, biomolecule detection method, and biochip
abstract The present invention provides a biosensor that detects biomolecules in a sample with high accuracy and high sensitivity. The present invention is a biosensor for detecting a biomolecule in a sample, a substrate, a magnetoresistive effect element whose resistance value changes according to the direction of an input magnetic field, and the magnetoresistive effect A soft magnetic thin film disposed adjacent to the element, and a protective film covering a surface of the soft magnetic thin film, wherein the protective film has a first affinity substance that recognizes the biomolecule on its outer surface. The soft magnetic thin film changes the direction of a magnetic field (applied magnetic field) applied in a substantially normal direction of the laminated surface, and forms a leakage magnetic field (detection magnetic field) at the end of the laminated surface of the soft magnetic thin film. A function of generating a magnetic field component in the magnetosensitive direction of the magnetoresistive effect element, and a function of transmitting the in-plane direction component of the stray magnetic field of the magnetic beads integrated on the soft magnetic thin film to the magnetoresistive effect element. Have.
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