abstract |
【Task】 To provide a nucleic acid complex, preferably a double-stranded nucleic acid complex, having an excellent effect of suppressing target gene expression. [Solution] An active portion comprising an antisense nucleic acid complementary to a transcript, eg, a transcript of a target gene, and a nucleic acid complementary to the nucleic acid, comprising a nucleic acid comprising DNA, preferably a nucleic acid based on DNA The above-mentioned problem is solved by using a nucleic acid complex containing, preferably a double-stranded nucleic acid complex. |