| abstract |
An object of the present invention is to provide a method for encapsulating a poorly water-soluble pharmacologically active substance in liposomes with high efficiency. A composition comprising a lipid having a phosphatidylcholine group, a cholesterol compound, a lipid having a phosphatidylethanolamine group, and a poorly water-soluble pharmacologically active substance, the lipid having a phosphatidylcholine group, a cholesterol compound, A composition comprising a lipid having a fatidylethanolamine group and a poorly water-soluble pharmacologically active substance in a molar ratio of 3-8: 2-7: 0.1-3: 0.001-5. |