http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017043656-A1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-04005 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57 |
filingDate | 2016-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2017043656-A1 |
titleOfInvention | Method for converting genome sequence of Gram-positive bacterium, which specifically converts nucleobase of targeted DNA sequence, and molecular complex used therefor |
abstract | The present invention relates to a method for modifying a targeted site of double-stranded DNA possessed by a Gram-positive bacterium, comprising a nucleic acid sequence recognition module that specifically binds to a target nucleotide sequence in a selected double-stranded DNA; The complex bound to the nucleobase converting enzyme is brought into contact with the double-stranded DNA, and the targeted DNA is obtained without cleaving at least one strand of the double-stranded DNA at the targeted site. Converting or deleting one or more nucleotides of a site into one or more other nucleotides, or inserting one or more nucleotides into the targeted site, the double-stranded DNA and the complex; Is provided by introducing a nucleic acid encoding the complex into the Gram-positive bacterium. The present invention also provides a complex in which a nucleic acid sequence recognition module that specifically binds to a target nucleotide sequence in double-stranded DNA possessed by a Gram-positive bacterium and a nucleobase converting enzyme for use in the method is bound. provide. |
priorityDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 280.