abstract |
Diseases involving Nav1.7, such as neuropathic pain, nociceptive pain, inflammatory pain, small-fiber neuropathy, limb erythema pain, paroxysmal pain, dysuria or multiple sclerosis Providing therapeutic drugs for diseases. Formula (I): [wherein R1a, R1b, R1c and R1d represent hydrogen, halogen, cyano, C1-4 alkyl, C1-4 alkoxy and the like, provided that at least one of R1a, R1b, R1c or R1d Represents C 6-10 aryl, C 6-10 aryloxy, etc., R 2 and R 3 represent hydrogen, C 1-6 alkyl, C 3-10 cycloalkyl, etc., and R 4 represents hydrogen, C 1-6 alkyl, C 3-7 cyclo A compound represented by the following formula: m represents alkyl, m represents 1, 2 or 3, L represents CR7R8, R7 and R8 represent hydrogen, hydroxyl group, C1-4 alkyl, C1-4 alkoxy, etc. Or a pharmaceutically acceptable salt thereof. |