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filingDate 2016-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2017034031-A1
titleOfInvention Diagnostic method for autoimmune disease, biomarker for diagnosis of autoimmune disease, and preventive or therapeutic agent for autoimmune disease
abstract The present invention is a method for diagnosing an autoimmune disease, comprising measuring a relative abundance of bacteria contained in a stool sample collected from a subject, and performing the following (1) or (2): The present invention relates to a diagnostic method. (1) The relative abundance of a bacterium having a nucleotide sequence of 16S ribosomal RNA gene having 99% or more identity with the nucleotide sequence specified by SEQ ID NO: 3 or 4 is compared with the relative abundance in healthy individuals In many cases, it is determined that the subject is suffering from or has a high risk of suffering from an autoimmune disease. (2) The relative abundance of a bacterium having a nucleotide sequence of 16S ribosomal RNA gene having 99% or more identity with any of the nucleotide sequences specified by SEQ ID NOs: 5 to 23 is compared with the relative abundance in healthy individuals If so, it is determined that the subject is suffering from or at high risk of suffering from an autoimmune disease.
priorityDate 2015-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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