http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2016159374-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G75-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-067 |
| filingDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2016159374-A1 |
| titleOfInvention | Method for producing glycoside compound |
| abstract | In the present invention, a thioether compound represented by the general formula (103) and an alcohol compound represented by the general formula (105) are subjected to a coupling reaction in the presence of a halogenating agent, a desiccant and a Lewis acid, A step of obtaining a thioether compound represented by the general formula (104) by distillation in the presence of at least one additive selected from a sulfur-containing antioxidant and a maleimide group-containing compound (step 0); and a halogenating agent In the presence of a desiccant and a Lewis acid, A step of obtaining a glycoside compound represented by the general formula (Ib) by coupling the glycoside compound represented by the general formula (Ia) and the thioether compound represented by the general formula (104) (step 1). And a method for producing a glycoside compound represented by the general formula (I) or a salt thereof. This method makes it possible to produce phosphoramidites suitable for nucleic acid production (synthesis) more efficiently and with high purity (each compound is as defined in the specification). |
| priorityDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 247.