http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2016129444-A1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2016129444-A1 |
titleOfInvention | Antibody-binding phosphor-integrated nanoparticles, method for producing antibody-binding phosphor-integrated nanoparticles, and immunostaining kit |
abstract | [Problem] The present invention has an object to provide antibody-binding phosphor-integrated nanoparticles, a method for producing antibody-binding phosphor-integrated nanoparticles, and an immunostaining reagent kit capable of suppressing a decrease in staining efficiency of immunostaining due to molecular aggregation. To do. [Solution] An SH group generated by reducing an antibody and phosphor-integrated nanoparticles by reducing a disulfide bond (-SS-) of the antibody; and a binding group on the surface of the phosphor-integrated nanoparticles; The antibody-bound phosphor-aggregated nanoparticles bound by the reaction of (2), wherein streptavidin in which disulfide bonds are reduced to SH groups using 2-iminothiolane is within the unit area of the surface of the phosphor-aggregated nanoparticles. An antibody-binding phosphor, wherein when the number that can be bound to a predetermined number of binding groups is expressed as nmol, the number of the antibodies bound to the predetermined number of binding groups is 2 nmol or more. Integrated nanoparticles. |
priorityDate | 2015-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 836.