http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2016068226-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96494 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2015-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2016068226-A1 |
| titleOfInvention | Rheumatoid arthritis marker |
| abstract | It is an object of the present invention to provide a method for evaluating the disease activity of rheumatoid arthritis and a kit therefor with a simple method with high sensitivity and reliability. Furthermore, the present invention provides an accurate diagnostic method for rheumatoid polymyalgia and relapsing polychondritis, which are similar rheumatic diseases, and a method for distinguishing from rheumatoid arthritis, and a kit therefor. The present invention provides a Jacalin-binding O-linked glycan epitope as a negative rheumatoid arthritis diagnostic marker, and the reciprocal of the amount of binding between MMP-3 and Jacalin in the blood, -More accurate assessment of disease status by more objectively determining the disease activity of rheumatoid arthritis based on the amount of change in the amount of MMP-3 combined with the amount of MMP-3 in the blood combined with ABA, ACA or ACG Made possible. In addition, we found that LEL or STL-reactive sugar chains on MMP-3 in blood can be used as a sugar chain marker for the diagnosis of rheumatic polymyalgia and relapsing polychondritis. An accurate diagnostic method for polychondritis was provided. Furthermore, rheumatoid arthritis that can be differentiated from similar rheumatic diseases by measuring the ratio of the amount of LEL or STL binding on MMP-3 in the blood to the amount of binding of Jacalin or ACG on MMP-3. An accurate diagnostic method was provided. |
| priorityDate | 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 540.