| abstract |
The present invention relates to a novel pyrrolidine compound having melanocortin receptor agonist activity or a pharmacologically acceptable salt thereof and a pharmaceutical use thereof. The present invention relates to general formula [I] [Wherein, ring A represents an optionally substituted aryl group, etc .; R 1 represents an optionally substituted alkyl group, etc .; R 2 represents a halogen atom, etc .; R 3 represents a substituted group] Or an alkyl group substituted with an aryl group, and R 4 is a hydrogen atom or the like; or R 3 and R 4 are bonded to each other at the end, and together with the nitrogen atom to which they are bonded, a partial Form a nitrogen-containing aliphatic heterocyclic ring which may contain a double bond or may be substituted, or a pharmaceutically acceptable salt thereof. |