| abstract |
Provided is an anti-aging skin external composition for preventing or improving skin appearance troubles such as wrinkles, fine wrinkles, loosening, and spots due to aging and aging, and maintaining or enhancing the barrier function in the skin. By providing an anti-aging skin external preparation comprising one or more selected from adenosine N1-oxide 5′-phosphate, an analog thereof and a salt thereof as an active ingredient To solve. |