http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2014196557-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 |
| filingDate | 2014-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2014196557-A1 |
| titleOfInvention | Process for producing optically active 2-[(1,2,3,6-tetrahydropyridin-4-yl) methyl] -2-fluoro-2,3-dihydroinden-1-one |
| abstract | An optically active 4-[(2-fluoro-1-indanone) -2-yl] methylpiperidine is obtained. (1,2,3,6-Tetrahydropyridin-4-yl) methyl 2-fluoro-2,3-dihydro-1-oxo-1H-indene-2 represented by the following general formula (1) -Carboxylate is subjected to allylation reaction with intramolecular decarboxylation in the presence of a chiral ligand and a transition metal catalyst to give an optically active 2-[(1 , 2,3,6-tetrahydropyridin-4-yl) methyl] -2-fluoro-2,3-dihydroinden-1-one. Optically active 4-[(2-fluoro-1-indanone) -2-yl] methylpiperidine can be obtained by reducing the produced compound of the general formula (2). [Selection figure] None |
| priorityDate | 2013-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 233.