| abstract |
The present invention provides an improved three-dimensional artificial tissue and its composite tissue, and a method for producing the same. The present invention substantially relates to a transplantable artificial tissue composed of a mesenchymal stem cell derived from pluripotent stem cells or an equivalent cell thereof, and an extracellular matrix derived from the cell, and an osteochondral defect. A composite tissue comprising the artificial tissue according to claim 1 and an artificial bone for treating or preventing a disease, disorder, or condition, wherein the artificial bone is based on a depth of a bone defect in the osteochondral defect. A composite tissue, as well as a method for its production, are provided that are also small in size. |