http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2014021240-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate | 2013-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2014021240-A1 |
| titleOfInvention | Capturing agent containing protein comprising tandem multimer of extracellular domain mutant of protein G |
| abstract | The object of the present invention is to bind to the Fc region of an immunoglobulin in a weakly acidic region as compared with a protein containing the extracellular domain of wild-type protein G without impairing the high antibody binding activity in the neutral region. And / or providing an excellent protein having a lower binding property to the Fab region, and easily capturing and recovering the antibody without denaturation by using a capture agent and a column using the protein. In the present invention, a protein composed of a tandem multimer of an extracellular membrane variant having an activity of binding to a protein having an Fc region of immunoglobulin G is immobilized on a water-insoluble solid phase support mainly via an amino group. The present invention relates to an antibody, a capture agent for a protein having immunoglobulin G or an Fc region of immunoglobulin G, and a chromatography column for protein separation and purification packed with the capture agent. |
| priorityDate | 2012-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 230.