abstract |
Provision of orally administrable and low toxicity somatostatin receptor subtype 2 agonist. Formula (I): [Wherein all symbols have the same meaning as defined in the specification. ] , Its N-oxide, its solvate, or their prodrugs are non-peptide low molecular weight compounds having potent somatostatin receptor subtype 2 agonist activity, and thus can be administered orally. Because it is possible and has low toxicity, it is useful for the prevention and / or treatment of somatostatin-related diseases such as acromegaly and gastrointestinal obstruction. |