http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2013039000-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24011 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-55 |
| filingDate | 2012-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2013039000-A1 |
| titleOfInvention | Pharmaceuticals for the prevention or treatment of Alzheimer's disease |
| abstract | Provide therapeutics for Alzheimer's disease. The therapeutic agent includes a membrane vesicle (exosome) of adipose tissue-derived mesenchymal stem cells, and the membrane vesicle (exosome) includes neprilysin. The inventors' research has revealed that exosomes secreted from human adipose tissue-derived mesenchymal stem cells contain neprilysin that degrades amyloid β, a pathogenic protein of Alzheimer's disease. When exosomes secreted from human adipose tissue-derived mesenchymal stem cells were administered to the brains of Alzheimer's disease model mice, the production of amyloid β was suppressed. |
| priorityDate | 2011-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.