abstract |
A cancer antigen protein specifically expressed on the surface of a cancer cell is identified, and an antibody targeting it and use of the antibody as a therapeutic and / or prophylactic agent for cancer are provided. An antibody or fragment thereof comprising a heavy chain variable region comprising SEQ ID NOs: 5, 6 and 7 and a light chain variable region comprising SEQ ID NOs: 9, 10 and 11, and having immunoreactivity with the CAPRIN-1 protein; And a pharmaceutical composition for treating and / or preventing cancer comprising the antibody or fragment as an active ingredient. |