| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
| filingDate |
2012-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2014-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-WO2012150663-A1 |
| titleOfInvention |
Improved sugar-coated liposome composition |
| abstract |
【Task】 This invention makes it a subject to provide the formulation which has the effect which promotes cellular immunity more in the utilization as an adjuvant and the cancellation | release method of an immunosuppression mechanism. [Solution] Administration with MHC class I antigens provides sugar-coated liposomes (especially mannose-coated liposomes) that can activate CTL in an MHC class II antigen-independent (CD4 + T cell-independent) manner. In particular, a sugar-coated liposome is provided in which the particle size of the sugar-coated liposome is 100 to 1100 nm and / or the molar ratio of sugar-modified lipid to lipid is 0.00075 to 0.075. [Selection figure] None |
| priorityDate |
2011-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |