http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2012102260-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2012-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2012102260-A1 |
| titleOfInvention | Nucleic acid molecule polymorphism identification method |
| abstract | The present invention provides a method for identifying a polymorphism of a nucleic acid in a sample solution in which the concentration or number density of the nucleic acid to be observed is lower than that of a conventional optical analysis technique. That is, the present invention provides a first nucleic acid probe that is labeled with a fluorescent substance and specifically hybridizes with a single-stranded nucleic acid molecule having a first type base sequence in a polymorphic sequence, and an analysis object A nucleic acid molecule in the sample solution is denatured and then associated, and is labeled with a fluorescent substance and has a base sequence different from that of the first nucleic acid probe. A step of preparing a sample solution containing the nucleic acid probe of 2 and the nucleic acid to be analyzed, associating the nucleic acid molecules in the sample solution, and molecules of the aggregate containing the first nucleic acid probe in each sample solution The number of molecules of the aggregate including the number and the second nucleic acid probe is calculated by a scanning molecule counting method, and the step of identifying the polymorphism of the nucleic acid to be analyzed based on the calculation result It relates to the type identification method. |
| priorityDate | 2011-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.