http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2012081433-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate | 2011-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2012081433-A1 |
titleOfInvention | Amyloid β neuropathy biomarker |
abstract | To provide a novel biomarker for testing amyloid β neuropathy such as Alzheimer's disease. A method for examining Alzheimer's disease, comprising measuring the amount of MFG-E8 protein in a blood, serum or plasma sample obtained from a subject or a test animal, and using the obtained measurement value as Alzheimer's disease. Disclosed is a method characterized by using as an index of diagnosis. MFG-E8 protein in the culture supernatant of dementia model mouse brain cells stimulated with A [beta] 42, has been found as a protein that binds to the Ca 2+ dependent manner phosphatidylserine. Furthermore, it was revealed that the level of MFG-E8 protein was elevated in Alzheimer's disease patients. |
priorityDate | 2010-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.