http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2012073857-A1

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-067
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
filingDate 2011-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2012073857-A1
titleOfInvention 2'-O-modified RNA
abstract PROBLEM TO BE SOLVED: To provide 2'-modified ribonucleoside and the like exhibiting high duplex forming ability. [MEANS FOR SOLVING PROBLEMS] Basically, a modified product such as a ribonucleoside having an alkoxymethyl-based protecting group introduces a halogen atom into the protecting group moiety as a substituent, thereby providing a high ability to form a double chain. Based on the knowledge of the example that it was possible to give. As described above, a modified RNA having an alkoxymethyl-based protecting group had a low duplex forming ability. However, the modified RNA having a halogen-substituted alkoxymethyl-based protecting group of the present invention showed the same high duplex forming ability as the 2′-O-methyl modified nucleic acid. [Selection] Figure 1
priorityDate 2010-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 24.