| abstract |
It is an object of the present invention to provide a β-sheet structure protein imaging probe for the diagnosis of conformation disease, in particular, a disease mainly characterized by tau protein accumulation in the brain (tauopathy: tauopathy), for example, Alzheimer's disease. To do. Further, the present invention is a compound that has high specificity for tau, can image tau with good sensitivity, has high brain migration, low or no bone accumulation, and low or no toxicity The purpose is to provide. The present invention relates to a compound represented by formula (I) (wherein A, R 1 , R 2 and R 3 and the like are as defined herein) or a pharmaceutically acceptable salt or solvent thereof The above problem is solved by providing a Japanese product. |