http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2011122468-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 2011-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2011122468-A1 |
| titleOfInvention | Pyripyropene derivative stable to metabolic enzymes showing ACAT2 inhibitory activity |
| abstract | A compound represented by the following general formula and salts, solvates and hydrates thereof which are effective for the prevention or treatment of arteriosclerosis having a mechanism of action different from that of statin drugs. Embedded image In the formula, R 1 represents an aliphatic, alicyclic or aromatic acyloxy group, or a group represented by the formula: —O—CH (R 7 ) —R 8 , wherein R 7 represents a lower alkoxy group. R 8 represents an aryl group, R 2 and R 3 represent R 2 represents a carboxyl group, a lower alkoxycarbonyl group, an arylmethylcarbamoyl group, or a —CH 2 -acyloxy group, and R 3 represents an aliphatic group. Means an aliphatic, alicyclic or aromatic acyloxy group, provided that at least one of R 4 and R 3 is a group other than an acetoxy group, or R 2 and R 3 together form —O—CH ( R 5 ) -O— means a group, and R 5 means an aryl group. |
| priorityDate | 2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.