abstract |
Useful as a preventive and / or therapeutic agent for skin diseases, Formula (I) {Wherein R 1 represents -NR 1a R 1b (wherein R 1a and R 1b are the same or different and represent a hydrogen atom, aralkyl, etc.) R 2 represents the formula (Ya) [wherein k and m each represents an integer of 0 to 2, n represents an integer of 0 to 4, L represents a single bond, etc., R 5 represents a halogen or the like, R 6 represents aryl or the like, X represents CR 8 (wherein R 8 represents a hydrogen atom or the like), R 7 represents a hydrogen atom or the like] or the like, R 3 is —SO 2 R 13a [wherein R 13a is a lower alkoxy, —NR 13d C (═O) R 13e (wherein R 13d represents a hydrogen atom, etc., R 13e represents a lower alkyl, etc.) Etc.] R 4 represents a hydrogen atom or the like. A pyrazolopyrimidine derivative represented by the following or a pharmaceutically acceptable salt thereof is provided. |