http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2011093294-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-02 |
| filingDate | 2011-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2011093294-A1 |
| titleOfInvention | Method for producing cephalosporin derivative |
| abstract | The objective cephalosporin derivative or alkali metal salt thereof having a high Z-form content is provided by an industrially advantageous method in a simple process. An aqueous solution of a compound represented by the following general formula (1) is brought into contact with activated carbon having an iodine adsorption performance measured according to JIS K-1474 of 1200 mg / g or more and a methylene blue adsorption performance of 250 ml / g or more, 7-amino-3-[(E / Z) -2- (4-methylthiazole-5-) represented by the following general formula (1) in which the content of the Z isomer represented by the following general formula (2) is improved. Yl) vinyl] -3-cephem-4-carboxylic acid or a first step thereof to obtain an alkali metal salt thereof, Next, a second step of reacting the compound represented by the formula (1) having an improved content of the Z-form obtained in the first step with the compound represented by the following general formula (3) is included. A method for producing a cephalosporin derivative represented by the following general formula (4a) or an alkali metal salt thereof: [Chemical 1] |
| priorityDate | 2010-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.