abstract |
The present invention effectively uses a substance that suppresses the expression or function of DEF6, specifically, an antisense nucleic acid, a ribozyme nucleic acid or a nucleic acid having RNAi activity against a transcription product of a gene encoding DEF6, an antibody that binds to DEF6, etc. An anti-tumor agent, in particular an angiogenesis inhibitor, which is contained as a component; and an angiogenesis inhibitor characterized by selecting a gene encoding DEF6 or a compound that decreases the expression level of DEF6 or the function of DEF6 A screening method is provided. |