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filingDate 2010-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2011018902-A1
titleOfInvention Pain control pharmaceutical composition
abstract The present invention provides the following general formula (1): [Ar-CH = CH-COO- (CH 2) n-NH-] m-HA (1) (In the formula, Ar represents a phenyl group which may have a substituent, n represents 2 or 3, HA represents a carboxy residue of hyaluronic acid, and m represents amidation with respect to all carboxyl groups of hyaluronic acid. And m is 3 to 50% of the total carboxyl groups.) A joint disease comprising hyaluronic acid crosslinked by cyclizing the double bond of the cinnamic acid moiety of the partially amidated hyaluronic acid represented by formula (II) and a pharmaceutically acceptable carrier The present invention relates to a pharmaceutical composition for suppressing pain in The pharmaceutical composition of the present invention has a rapid analgesic effect after administration, and is an intra-articular administration formulation that maintains an extremely long-term effect on human joint disease only by administration once instead of multiple conventional administrations It is.
priorityDate 2009-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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