| abstract |
The present invention is a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof capable of inhibiting a fibroblast growth factor receptor (FGFR) family kinase in cancer tissue. A: 5-10 membered heteroaryl, C 6-10 aryl R 1,2 : H, OH, X, CN, NO 2 , C 1-4 haloalkyl, C 1-6 alkyl, etc. (both (substituted) 3-10 Membered heterocyclyl, (substituted) 5-10 membered heteroaryl may be formed> R 3 : H, C 1-5 alkyl, C 6-10 aryl C 1-5 alkyl, C 1-4 haloalkyl R 4 : H, X, C 1-3 alkyl, C 1-4 haloalkyl, OH, CN, NO 2 etc. |