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publicationNumber JP-WO2010150578-A1
titleOfInvention Imported lymphatic inflow detection method and specific cell identification method
abstract A site where metastatic cancer cells may exist in the sentinel lymph node is accurately detected. Quantum dots are injected in the vicinity of cancer in the living body, the position of the sentinel lymph node is determined by fluorescence, and the sentinel lymph node is removed. Structural analysis is performed on the sentinel lymph node extracted in a state where the quantum dots are injected by precise fluorescence measurement using a confocal fluorescence microscope for single molecule observation. Specifically, the fluorescence intensity is measured for each of a plurality of sites in the sentinel lymph node, and one or a plurality of sites in order from the highest fluorescence intensity among the plurality of measured sites is used as the import lymphatic inflow portion. To detect.
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