http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2010104106-A1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C247-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-24 |
filingDate | 2010-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2010104106-A1 |
titleOfInvention | Method for producing optically active diamine derivative |
abstract | The challenge is to provide key intermediates for the production of FXa inhibitors. The solution is a method for industrially producing the compound (1) and the compound (4), [First operation]: A quaternary ammonium salt and a metal azide salt are added to water to prepare an aqueous solution of an azide reagent complex composed of a quaternary ammonium salt-metal azide salt. Subsequently, the aqueous solution is mixed with an aromatic hydrocarbon solvent. Dehydration treatment is used to obtain an aromatic hydrocarbon solvent mixture of an azide reagent complex comprising a quaternary ammonium salt-metal azide having a water content of 0.2% or less; Then [Second operation]: Adding compound (2) (L represents a leaving group) to the mixed solution prepared in the above [first operation]; Is a manufacturing method characterized by |
priorityDate | 2009-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.