http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2010103684-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-787 |
| filingDate | 2009-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-WO2010103684-A1 |
| titleOfInvention | Sequence-specific expression regulator targeting MYC downstream gene, and method for determining target or target group of MYC downstream gene |
| abstract | A pyrrole-imidazole polyamide containing an N-methylpyrrole unit (hereinafter also referred to as Py), an N-methylimidazole unit (hereinafter also referred to as Im), and a γ-aminobutyric acid unit, which is an E of a MYC downstream gene having a predetermined base sequence -A part or all of a BOX region sequence and a predetermined sequence which is an antisense sequence thereof, and further a sequence containing 1-2 base sequences upstream and / or downstream of the E-BOX region and a complementary strand thereto In the minor groove of the double helix region (hereinafter referred to as the target region), it can be folded at the site of the γ-aminobutyric acid unit to take a U-shaped conformation. For CG base pairs, Py / Im pairs correspond to Im / Py pairs for GC base pairs, and Py / Py pairs correspond to AT base pairs and TA base pairs, respectively. A drug comprising the pyrrole-imidazole polyamide. |
| priorityDate | 2009-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 391.