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filingDate 2009-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2012-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-WO2010064435-A1
titleOfInvention Method for measuring cystatin C in human body fluid
abstract Compared to conventional measurement methods that used a large amount of low-specificity polyclonal antibodies and monoclonal antibodies that have high specificity but weak aggregation properties, they are highly specific, low-cost and easy to automate in human body fluids. A particle-enhanced immunoassay method for cystatin C is provided. High-affinity anti-human cystatin C monoclonal antibody was combined with antibody-sensitized particles in which an anti-human cystatin C monoclonal antibody having a different recognition site and relatively low affinity was independently bound to insoluble carrier particles. A method for measuring cystatin C specific in a human body fluid, wherein the binding amount of anti-human cystatin C monoclonal to the weight of each antibody-sensitized particle is less than 5% by weight.
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