| abstract |
An object of the present invention is to provide a composition for local anesthesia to be added to a local anesthetic, which maintains the local anesthetic effect and has high safety. According to a composition for local anesthesia comprising an agent that antagonizes the systemic action of adrenaline, ie an α2 receptor agonist. By adding an α2 receptor agonist to a local anesthetic together with adrenaline or a salt thereof, the amount of adrenaline added can be reduced compared to a single agent of adrenaline or a salt thereof, and as a result, the local anesthetic effect is sustained. Highly safe local anesthesia can be performed. |