http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2010047296-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6512 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6512 |
filingDate | 2009-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-WO2010047296-A1 |
titleOfInvention | Method for producing novel pyrimidine derivative and intermediate of HMG-CoA reductase inhibitor |
abstract | An object of the present application is to provide a method for producing a novel pyrimidine derivative from a compound that is inexpensive and easily available industrially, and a method for producing an important intermediate of an HMG-CoA reductase inhibitor. This subject is, for example, a phosphonic acid ester represented by the following formula (3) obtained by reacting a compound represented by the following formula (1) with a compound represented by (OR 1 ) 3 P, and the following formula: This is solved by reacting the compound represented by (4) in the presence of a base to obtain an HMG-CoA reductase inhibitor intermediate represented by the following formula (5). [Chemical 1] |
priorityDate | 2008-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.