| abstract |
The present invention provides a protein crosslinking inhibitor comprising a compound represented by any one of the following general formulas (1) to (13) or a pharmaceutically acceptable salt thereof. (1) R 3 - [- X-B (ZR 1) -Y-B (ZR 2) -W-] n -R 4, (2) R 3 - [- X-B (ZR 1) -Y-] n -R 4, (3) R 3 - [- B (ZR 1) -Y-B (ZR 2) -W-] n -R 4, (4) R 3 - [- X-B (ZR 1) -] n -R 4, (5) R 3 - [- B (ZR 2) -W-] n -R 4, (6) R 3 -X-B (ZR 1) -T [B (ZR 2) -W-R 4] 2, (7) R 3 -B (OH ) 2, (8) R 3 -B (ZR 1) -X-B (ZR 2) -R 4, (9) R 3 -B (R 1) -O-B (R 2) -R 4, (10) R 3 - [- X-B (ZR 1) -Y-B (ZR 2) -] n -R 4, (11) R 3 - [- X-B (ZR 1) -Y-B (ZR 2) -W-Q-] n -R 4, (12) R 3 - [- P-X-B (ZR 1) -Y-B (ZR 2) -W-] n -R 4, (13) [R 3 -X- B (ZR 1) -Y] 2 B (ZR 2), [Wherein each symbol has the same definition as in the specification. ] |