abstract |
An object of the present invention is to provide a drug carrier that mainly contains a polyethylene glycol-modified phospholipid and a cationic lipid, and contains the polyethylene glycol-modified phospholipid in a specific concentration range. is there. The present invention relates to a polyethylene glycol-modified phospholipid represented by the following general formula (I) or a pharmaceutically acceptable salt thereof: [In formula (I), X represents the following (II) or (III). n represents an integer of 30 to 150. ], [In the formulas (II) and (III), R 1 represents a saturated linear fatty acid residue having 17 to 22 carbon atoms. And 2-O- (2-diethylaminoethyl) carbamoyl-1,3-O-dioleoylglycerol and a polyethylene glycol-modified phospholipid represented by the general formula (I) in a drug carrier The present invention relates to a drug-retaining drug carrier that is contained in the range of 30 to 50% by weight based on the total weight of the lipid. [Selection] Figure 4 |