| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2323-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2323-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2325-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2325-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2325-36 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D69-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D71-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D69-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D71-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D61-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D69-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D67-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D61-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D61-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D61-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D63-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate |
2009-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2011-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-WO2009141965-A1 |
| titleOfInvention |
Filtration method |
| abstract |
The present invention provides a filtration method for a virus removal step in a protein formulation production process under conditions in which an intermediate product of a protein formulation having a high protein concentration is passed through a virus removal filter at a high pressure. A least the inlet has a nozzle fitting structure having a higher pressure resistance 600 kPa, with a viral removal filter effective membrane area is 0.0001 m 2 or more 0.03 m 2 or less of the virus removal membrane, the The protein preparation intermediate product whose protein concentration has been increased to 20 mg / ml or more and 100 mg / ml or less in the virus removal filter, the inlet pressure of the protein preparation intermediate product is 150 kPa or more and 600 kPa or less, and the average protein filtration rate is 1.0 kg. A filtration method of obtaining a filtrate of an intermediate product of a protein preparation having a virus removal rate LRV ≧ 3 by flowing for 1 to 5 hours as a filtration time under the conditions of / m 2 / Hr or more. [Selection figure] None |
| priorityDate |
2008-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |