abstract |
The following general formula (I), (In the formula, R 1 and R 2 represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkyl group having 1 to 8 carbon atoms substituted with a halogen atom, etc .; R 3 , R 4 , R 5 and R 6 represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, and the like, X represents a sulfur atom or the like, Y represents an oxygen atom, a bond, etc. p represents 0 or 1, A represents an oxygen atom, CH 2 , N—NH 2 or the like, B represents a benzene ring which may have a substituent when p is 1, B represents a condensed ring selected from benzisoxazole ring and the like which may have a substituent when p is 0. m represents an integer of 1 to 4, And n represents the integer of 0-5. ) Or a pharmacologically acceptable salt thereof is used as an activator of PPAR. |