abstract |
An object of the present invention is to establish a system for reliably differentiating ES cells into hepatocytes. According to the present invention, an ES cell derived from a mammal in the presence of M15 cells, activin, and There is provided a method for inducing differentiation from ES cells to hepatocytes, comprising culturing in the presence of bFGF followed by culturing in the presence of dexamethasone, HGF, and Oncostatin M. |